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Olga Aldoshina

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Review 2026

Current advances in mammalian genome modification technology using the CRISPR-Cas9 principle

This article synthesizes contemporary advancements in CRISPR-mediated mammalian genome modification, detailing core mechanisms – such as guide RNA and the Cas9 endonuclease – alongside next-generation modalities, including base and prime editing.

Olga Aldoshina, Dmitriy Lazarev, E. Smirnova · 0 citations