Narrative Review of Pathogenetic Mechanisms and Diagnostic Biomarkers in Adipose Tissue Remodelling and Adipokine Dysregulation in Lipedema
Aim: This narrative review summarises evidence on pathogenetic mechanisms of adipose tissue remodelling and adipokine dysregulation in lipedema, focusing on adipocyte hypertrophy and hyperplasia, fibrosis, microcirculatory and lymphatic dysfunction, immune-cell alterations, and diagnostic biomarkers. Methods: We conduc...