Liquid chromatography–hydrogen/deuterium exchange–mass spectrometry (LC-HDX-MS) provides orthogonal structural information that complements conventional LC-MS and improves confidence in small-molecule structural elucidation. Although HDX-MS is well established in protein research, its application to small molecules rem...
Tomáš Čajka, J. Hricko, Lucie Rudl Kulhavá et al.· Analytica· 0 citations
Despite milk being a global dietary staple, the molecular basis of its health-relevant bioactivity and the factors governing fine-scale compositional variation remain poorly understood. Here, we present an integrated seven-layer omics characterization of 60 US retail milk samples from ten geographic regions, combining...
Cheng-En Tan, M. Barboza, Pagkratios Tagkopoulos et al.· 0 citations
Overall, plasma can only serve as limited proxy for tissue metabolism, and several potential blood biomarkers were discovered as concordant in plasma and tissues in lifespan-extending interventions.
Sara Greenfield, C. Brown, Oliver Fiehn· Metabolites· 0 citations
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