Pseudomonas aeruginosa relies on the redox cofactor pyrroloquinoline quinone (PQQ) for efficient glucose and ethanol metabolism via periplasmic dehydrogenases (Gcd and ExaA). While PQQ biosynthesis is well-characterized, its uptake mechanisms remain unclear. Here, we identify PA2289 (PqqU), a TonB-dependent transporter...
C. Paschalidis, Manon Ferry, Anne-Eloïse Revillot-Schmidt et al.· FEMS Microbiology Letters· 0 citations
Pseudomonas aeruginosa employs a repertoire of TonB-dependent transporters (TBDTs) to acquire essential nutrients, such as iron-siderophore complexes, enabling its adaptation to diverse and often hostile environments. While the roles of some TBDTs in virulence and metal acquisition are well-established, many remain poo...
With 21 outer-membrane transporters dedicated to iron acquisition, Pseudomonas aeruginosa possesses an extensive toolkit for securing this essential nutrient, but activates the expression only of those relevant to its immediate environment. Eighteen of these pathways rely on siderophores, two produced by P. aeruginosa...
Florian Volck, Anne-Eloïse Revillot-Schmidt, Thibaut Hubert et al.· Proceedings of the National...· 0 citations
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