319. Mycobacterium avium Subsp. Paratuberculosis Infection Suppresses Purinergic Signaling and Reshapes Immune, Oxidative, and Apoptosis Pathways in Peripheral Blood Mononuclear Cells of Goats.
Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic enteric infection that leads to significant production losses and remains a major challenge to livestock health and productivity. Despite extensive research, the early molecular mechanisms underlying host immune dysregulation d...