Omed Qadir Ibrahim

Halogenated Phenylsulfamates as hCA IX Inhibitors: In Silico Evaluation of Dynamic Stability and Pharmacokinetic Safety

Therapeutic targeting of human Carbonic Anhydrase IX (hCA IX) is critical for cancer treatment, as the enzyme regulates pH homeostasis and facilitates the survival of hypoxic tumor cells. This in silico study presents a multi‐layered computational investigation of a series of 4‐halogenated phenylsulfamates (4: Cl, 5:...