Author

Orçun Can

3 papers indexed here

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Open access Aug 2026

Development of a biomarker-guided chemotherapy response model using combined CEA and CA19-9 profiles in esophageal cancer: A real-world pharmacotherapeutic study.

BACKGROUND Esophageal adenocarcinoma is associated with poor survival despite advances in systemic therapy. Readily available serum biomarkers may improve risk stratification; however, their combined role in biomarker-guided treatment decisions remains insufficiently investigated. OBJECTIVES To evaluate the prognosti...

Orçun Can, A. Sakin · Pakistan Journal of Pharmace... · 0 citations

Open access Aug 2026

TOPM (Translational Oncotype Prediction Model): Development and Internal Validation of an Interpretable Clinicopathological Model for Pre-Test Estimation of High Oncotype DX Recurrence Score in Early Hormone Receptor–Positive, HER2-negative Breast Cancer

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Orçun Can, C. Uras · International Journal of Dru... · 0 citations

Open access Aug 2026

Real-world effectiveness of trastuzumab deruxtecan in heavily pretreated her2-positive metastatic breast cancer: A single-center experience

Aim: Trastuzumab deruxtecan (T-DXd) has shown substantial activity in trials of HER2-positive metastatic breast cancer (mBC), but real-world data in heavily pretreated patients, in those with CNS metastases, and in patients started at reduced doses remain limited. To evaluate real-world efficacy and safety of T-DXd in...

Orçun Can, O. Demir · Medical Journal of Western B... · 0 citations