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Author

Oriana Di Domenico

2 papers indexed here

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Review Open access Sep 2026

The Emerging Role of Ferroptosis in Pediatric Cancer Biology and Therapy

Ferroptosis is a regulated form of cell death caused by iron-dependent membrane lipid peroxidation. Iron metabolism, membrane lipid composition, cellular metabolic pathways, and antioxidant defense systems regulate ferroptosis. Recently, ferroptosis has attracted interest as a target in cancer therapy, in particular ca...

A. Di Paola, M. Marrapodi, Giuseppe Di Feo et al. · 0 citations
Review Open access Sep 2026

The Osteosarcoma Tumor Microenvironment: From Cellular Interactions to Advanced Preclinical Models

Simple Summary Osteosarcoma (OS) is a rare and aggressive bone cancer that mainly affects children and adolescents. Developing new and effective treatments is challenging because OS is a complex disease that interacts with the tumor microenvironment. Preclinical models are essential for studying tumor biology, growth,...

Giuseppe Di Feo, A. Di Paola, Oriana Di Domenico et al. · 0 citations

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