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Aug 2026

Subthreshold early white-matter hyperintensity increase predicts accelerated hippocampal and whole-brain atrophy in anti-amyloid-β immunotherapy

Background Anti-amyloid-β (anti-Aβ) therapy slows cognitive decline but paradoxically accelerates whole-brain gray matter atrophy, complicating outcome prediction. Objective To identify early imaging markers that predict long-term prognoses. Methods This longitudinal cohort study prospectively enrolled participants wit...

Shiori Amemiya, Hidemasa Takao, Shoya Matsumoto et al. · 0 citations
Open access Aug 2026

Discrepancy between the Radiographic Screening by Magnetic Resonance Imaging and Histopathologic Diagnosis of Vascular Malformations

Objectives Although magnetic resonance imaging (MRI) is widely used to evaluate extracranial vascular anomalies (VAs), its diagnostic accuracy remains uncertain. Methods We retrospectively assessed MRI accuracy for VAs and identified nonvascular lesions mimicking them. Patients who underwent surgical resection for susp...

M. Shiraishi, Kou Fujisawa, Yoichi Yasunaga et al. · 0 citations
Open access 2026

Brain Amyloid Burden Mapping Using MR Fingerprinting Aided by Deep Learning.

The proposed framework enables non-invasive Aβ mapping using a clinically feasible MRI protocol and may support repeated assessment for monitoring during anti-amyloid treatment.

Shohei Fujita, Y. Fushimi, Y. Otsuka et al. · 0 citations

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