An injectable kappa-carrageenan/konjac-glucomannan microgel platform for localized and controlled release of doxorubicin-loaded biomimetic nanoparticles.
Polysaccharide-based physical hydrogels are promising drug-delivery platforms due to their biocompatibility, tunable mechanical properties, and reversible crosslinking. However, bulk hydrogels may require in situ gelation for administration, while controlled release of nanoparticles larger than the hydrogel mesh remain...