Review
Open access
Sep 2026
Peptide-Based Molecular Glues for Targeted Protein Degradation
Targeted protein degradation has transformed drug discovery by replacing occupancy-driven inhibition with event-driven removal of disease-causing proteins, opening previously “undruggable” targets, including transcription factors, scaffolding proteins, and intrinsically disordered regions, to therapeutic intervention....
Walaa S. Aburayan, Ibrahim A. Alradwan, Beshair A. Alsaffar et al.
· Pharmaceutics · 0 citations