Ou Zhang

Unraveling Novel Prospective Inhibitors of Streptococcus pneumoniae Chorismate Synthase by Pharmacophore Screening, Docking Analysis and Molecular Dynamics Simulation Studies

Streptococcus pneumoniae is the major causative agent of community-acquired pneumonia, one of the main infectious diseases that causes inflammation in the alveoli and leads to significant morbidity and mortality across various age groups. Current treatments are challenged by multidrug-resistant strains of S. pneumoniae...