Transcriptomic profiling of paired clinical Leishmania (Mundinia) martiniquensis isolates reveals candidate pathways associated with reduced amphotericin B susceptibility and identifies a novel leishbuvirus variant
Leishmania ( Mundinia ) martiniquensis is an emerging cause of visceral leishmaniasis in Thailand, particularly among patients with advanced HIV infection. Reports of clinical relapse and treatment failure following amphotericin B (AmB) therapy have raised concerns regarding reduced drug susceptibility. Ho...