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Author

P. Bharatam

2 papers indexed here

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Sep 2026

Unveiling Neuroprotective Effects of a Triazole‐Based Compound in SH‐SY5Y Alzheimer's Disease‐Induced Cell Model

This study presents a novel triazole‐based compound as a highly promising therapeutic agent against Alzheimer's disease (AD), specifically targeting amyloid beta (A β ) toxicity in neuronal cells. Using a comprehensive blend of advanced spectroscopy, microscopy, and mass spectrometry techniques, we demonstrate th...

Khaja Moinuddin Shaik, Sakeel Ahmed, Mehak Sood et al. · 0 citations
Sep 2026

A pyridone-fused imidazo[1,2-a]pyridine hybrid binds to tubulin at the vinblastine site, depolymerizes microtubules and inhibits Cancer cell proliferation.

Tubulin remains a key target in anticancer therapy, motivating the development of structurally novel small-molecule inhibitors. The vinblastine-binding site on tubulin is a well-established and druggable pocket that accommodates structurally diverse ligands, including small-molecule inhibitors. Imidazo[1,2-a]pyridine r...

Mehak Sood, Tuhin Sarkar, Kanchan Chaurasiya et al. · 0 citations

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