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P. Faísca

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Open access Sep 2026

ADAM17 pathway promotes canine mammary tumor cell migration

ADAM17, also known as tumor necrosis factor-converting enzyme (TACE), is a pleiotropic protease that contributes to inflammation and cancer progression by activating epidermal growth factor receptor (EGFR) signaling and IL-6 trans-signaling, among other pathways. Because ADAM17 signaling remains poorly characteri...

André Luz, Joana Santos, J. Catarino et al. · 0 citations

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