Open access
Aug 2026
Kdm2a histone demethylase ablation restores anti-tumor immunogenicity in liver cancer.
BACKGROUND Liver cancer remains a major global challenge, with limited benefit from immune checkpoint inhibitors due to strong immune evasion. Emerging evidence indicates that chromatin modifiers shape tumor immunogenicity, but their roles in liver cancer immunity are not fully understood. METHODS We investigated the...
L. Gragnani, M. Lulli, Patrizio Caini et al.
· British Journal of Cancer · 0 citations