Author

P. Fernandez-Marcos

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Open access Oct 2026

Astrocyte-derived extracellular vesicles regulate proopiomelanocortin neurons and modify food intake and glucose metabolism.

BACKGROUND Astrocytes actively regulate hypothalamic circuits involved in energy balance, yet the mechanisms are not completely understood. Here we analyzed whether extracellular vesicles (EVs) released by hypothalamic astrocytes carry nutritionally sensitive signals that modulate metabolism, focusing on the potential...

Roberto Collado-Pérez, Alfonso Gómez-Romero, B. Stutz et al. · Metabolism: Clinical and Exp... · 0 citations

Open access Sep 2026

The Pentose Phosphate Pathway Regulates Myelo-Lymphoid Lineage Specification

Following infection, hematopoietic stem and progenitor cells (HSPCs) support immunity by increasing the rate of innate immune cell production but the metabolic cues that guide this process are unknown. To address this question, we combined in situ RNA barcoding and metabolomics approaches to perform metabolic state-fat...

J. Cosgrove, A. Donada, A. Lyne et al. · bioRxiv · 0 citations