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Pheng-Ann Heng

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Sep 2026

Label-aware Gaussian Splatting for Medical Volume Visualization in Mixed Reality.

Volume visualization is an important tool in exploring and understanding 3D medical data. Though the recent 3D Gaussian Splatting (3DGS) offers great potential for realtime high-quality medical volume visualization, directly applying 3DGS to visualize medical volume data often overlooks important anatomical structures,...

Rui-Yang Li, Cheng-Kun Li, Yu-Qi Tong et al. · 0 citations
Book Open access Aug 2026

The Forgetting-Learning Trade-off: Making Reinforcement Learning Work for Protein Language Models

Diagnostics reveal that RL on PLMs is governed by two reward properties: verifiability, whether the reward is a fixed environment or a learned surrogate vulnerable to distribution shift, and coverage, the fraction of sequence space giving an informative gradient.

Hanqun Cao, Hongrui Zhang, Junde Xu et al. · 0 citations
Book Open access Aug 2026

The Forgetting-Learning Trade-off: Making Reinforcement Learning Work for Protein Language Models

Reinforcement learning (RL) is increasingly applied to Protein Language Models (PLMs), yet its effectiveness varies across tasks, and standard metrics such as pass@k can rise even when the model's solvable problem set is shrinking. We introduce two capability-level diagnostics. The Expansion-Shrinkage Ratio (ESR) measu...

Hanqun Cao, Hongrui Zhang, Junde Xu et al. · 0 citations
#machine learning Open access Apr 2026

Accurate and task-agnostic modeling of enzymatic reactions through multimodal relational learning

ERAM aligns pre-trained molecular representations from Protein Language Model with the knowledge of enzyme catalysis by modeling enzymatic reactions as multi-relational data, and demonstrates its potential as a versatile and effective tool for enzyme catalysis research.

Yuansheng Huang, Lanqing Li, Wenjia Qian et al. · 2 citations

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