Author

P. J. Lucassen

3 papers indexed here

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Review Open access Sep 2026

Characterization of a metabolomics signature of the brain-health-promoting MIND diet in older persons

Background The MIND diet supports healthy cognitive aging. Yet, a challenge remains to identify individuals who do not adhere to the MIND and could be at risk for accelerated cognitive decline. A multi-metabolite biomarker panel could facilitate population screening. Objectives To determine and validate a blood metabol...

Jeanne Neuffer, R. González-Domínguez, S. Lefèvre-Arbogast et al. · The journal of prevention of... · 0 citations

Open access Oct 2026

The modulatory role of early-life experiences and sex on cognitive resilience in APP/PS1 mice over time

BACKGROUND Cognitive resilience to Alzheimer’s disease (AD) can be modelled in amyloid-expressing rodents through early handling (EH). This study investigated how EH and sex affect cognition and pathology over time. METHODS We assessed cognition (open field, object recognition test, Barnes maze) in 6- and 12-month-old...

M. Carrigan, Jeniffer Sanguino-Gómez, Melis Bayer-Var et al. · bioRxiv · 0 citations

Open access Sep 2026

Voluntary Physical Activity Modulates Brain ΔFOSB and Alters Coactivation Networks in Male and Female Mice

The findings suggest that long-term VWR induces widespread transcriptional alterations throughout the mouse brain, and functional and mechanistic follow-up studies are necessary to determine the impact of these alterations on stress regulation and cognition- and reward-related behavior.

Marene H. Hardonk, Rick Wenning, J. Stofberg et al. · eNeuro · 0 citations