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Open access Sep 2026

A topographic protomap in mouse subplate neurons precedes the onset of sensory experience

Within sensory systems, thalamic projections to layer 4 (L4) neurons establish precise neocortical topography. During development, thalamic axons first synapse onto subplate neurons (SPNs) beneath the cortical plate, however, how thalamic inputs are organized within the subplate is unknown. To examine SPN organization...

Travis A. Babola, Min-Zi Chang, Rachel Jun et al. · 0 citations
Open access Sep 2026

Brief Visual Deprivation Selectively Remodels Intracortical Inputs onto Layer 6 Corticothalamic Neurons in Primary Auditory Cortex.

Loss of one sensory modality can enhance processing in spared systems. Brief visual deprivation by dark exposure (DE) enhances auditory responses in the primary auditory cortex (A1) of adult mice, increasing firing rates, frequency selectivity, and behavioral performance. This enhancement is accompanied by reduced inhi...

Anthony T. Collins, Joseph P. Y. Kao, Hey-Kyoung Lee et al. · 0 citations
Open access Sep 2026

Granger sensori-behavioral functional taxonomy of neuronal ensemble activity from two-photon calcium imaging data.

Understanding how neuronal populations interact to encode and transform sensory information is a fundamental challenge in computational neuroscience. Most existing studies, however, study neural encoding, behavioral readout, and functional connectivity as disjoint problems. Two-photon calcium imaging enables simultaneo...

Sahar Khosravi, Nikolas A. Francis, P. Kanold et al. · 0 citations

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