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P. Karakasis

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Open access Oct 2026

Lipoprotein(a) and extent of coronary artery disease in patients undergoing PCI

A clear dose–response relationship was observed, with progressively higher odds of multivessel CAD across increasing Lp(a) quartiles, underscoring the contribution of Lp(a) to residual atherosclerotic risk beyond traditional cardiometabolic factors.

P. Theofilis, P. Vlachakis, A. Papanikolaou et al. · 0 citations
Review Open access Oct 2026

Non-Invasive Assessment of Coronary Microvascular Dysfunction: From Flow Quantification to Clinical Decision Making

Coronary microvascular dysfunction (CMD) is a major mechanism of myocardial ischemia and adverse cardiovascular outcomes in patients with angina or dyspnea, both in the absence and in the presence of obstructive coronary artery disease. Because the coronary microcirculation cannot be visualized directly with routine an...

Panagiotis Theofilis, A. Sakalidis, Kyriakos Dimitriadis et al. · 0 citations
Review Sep 2026

Complications After Permanent Pacemaker Implantation in Patients with Congenital Complete Atrioventricular Block: A Systematic Review and Meta-analysis.

BACKGROUND Congenital complete atrioventricular block (CCAVB) requires pacing from early life, yet the long-term burden of pacing-induced cardiomyopathy (PICM), mortality, and device-related complications has not been quantitatively synthesized. OBJECTIVE To determine the incidence of PICM, mortality, and device-rela...

P. Vlachakis, Panagiotis Theofilis, Maria Drakopoulou et al. · 0 citations
Review Open access Aug 2026

Switching from Vitamin K Antagonists to Direct Oral Anticoagulants in Frail Elderly Patients with Atrial Fibrillation: Systematic Review and Meta-Analysis

Background: Frailty complicates anticoagulation management in older patients with atrial fibrillation (AF), particularly when long-term vitamin K antagonist (VKA) therapy is already established. Whether switching to a direct oral anticoagulant (DOAC) improves outcomes in this setting remains uncertain, and guideline re...

P. Karakasis, Ricardo Gómez-Huelgas, Stylianos Tzeis et al. · 0 citations
Open access Aug 2026

The Association Between Serum Zinc Levels, Conventional and Novel Anthropometric Indices in Postmenopausal Women in Montenegro - a Cross-Sectional Study

Serum Zn levels were negatively correlated with conventional and novel anthropometric parameters and novel [body adiposity index (BAI), body roundness index (BRI), and cardiometabolic index (CMI)] anthropometric parameters in postmenopausal women.

Aleksandra Klisić, D. Djurovic, Nevena Cupara et al. · 0 citations
Review Open access Jul 2026

Multimodality echocardiography in structural heart disease: the evolving role of the interventional imager

This review outlines the expanding role of echocardiography across the spectrum of TSHIs, highlighting the importance of multimodality imaging, including three-dimensional transoesophageal echocardiography (3D TEE), intracardiac echocardiography (ICE) and fusion imaging techniques, for comprehensive structural evaluati...

N. Ktenopoulos, K. Vlasopoulou, P. Vlachakis et al. · 0 citations
Review Open access Jul 2026

Chronic Kidney Disease-Associated Cardiomyopathy: Mechanisms and Therapeutic Strategies.

A better understanding of CKD-CM pathogenesis is likely to enable early intervention and prevention, with successful outcomes measured by reduced progression to severe cardiomyopathy and lower cardiovascular mortality in CKD.

Konstantinos Grigoriou, Vasileios Lamprou, Anastasios Chatzichidiroglou et al. · 0 citations

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