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Author

P. Knaapen

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3 papers indexed here

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Open access Oct 2026

Advanced imaging to understand the relation between coronary microvascular dysfunction, coronary plaque burden, and vascular remodeling

Chronic coronary syndromes frequently occur in the absence of flow-limiting epicardial stenosis. Coronary microvascular dysfunction (CMD) is a key mechanism underlying angina with non-obstructive coronary arteries, yet its relationship with epicardial atherosclerosis remains incompletely understood. Emerging evid...

Y. Ding, R. Heok, P. Kamila et al. · 0 citations
Open access Oct 2026

Temporal associations of coronary plaque burden and myocardial perfusion with clinical outcomes

Coronary plaque burden and myocardial ischaemia are both recognised markers of risk in patients with suspected coronary artery disease (CAD). However, their relative impact on cardiovascular outcomes over time remains incompletely understood. To investigate the time-dependent prognostic value of quantitati...

J. Dahdal, T. Maaniitty, R. Jukema et al. · 0 citations
Open access Oct 2026

Integrated clinical and polygenic coronary artery disease risk score predicts 10-year progression of coronary artery plaque

Coronary artery disease (CAD) is highly heritable and clinical risk scores may insufficiently capture the full spectrum of individual risk. We investigated whether integrated polygenic risk score (iPRS) derived from a combination of genetic and clinical risk factors is associated with coronary plaque phenotypes a...

B. Weijs, N. Nurmohamed, D. Ratman et al. · 0 citations

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