Author

P. M. Kalligosfyri

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Review Open access Aug 2026

Diagnostic and prognostic role of circular RNAs: Analytical challenges and emerging opportunities

This review examines the analytical strategies used to detect and quantify circRNAs, including amplification-based methods (RT-qPCR, droplet digital PCR, and isothermal amplification), hybridization-based assays, sequencing approaches (short- and long-read RNA-seq), and emerging biosensor technologies.

A. Glovi, P. M. Kalligosfyri, A. Miglione et al. · iScience · 0 citations

Review Open access Jul 2026

Biosensors for Circular RNA Profiling in Biological Matrices

Early detection of many diseases remains difficult because they often develop silently over the course of years. Circular RNAs are now at the forefront as biomarker candidates with a covalently closed structure, making them highly stable with exonuclease resistance and long half-lives. With their disease-specific expre...

A. Glovi, P. Kalligosfyri, A. Miglione et al. · Analytical Chemistry · 0 citations