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P. Madeddu

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#software testing Preprint Oct 2026

Artificial Intelligence-Assisted Systems Biology Reconstruction of Diabetic Bone Marrow Dysfunction

An investigator led dialogue with artificial intelligence provides a foundation for a systems level understanding of diabetic bone marrow dysfunction and may facilitate the generation of testable hypotheses and the identification of mechanistic targets for coordinated restoration of disrupted niche interactions.

P. Madeddu · 0 citations
Open access Aug 2026

Artificial intelligence-assisted reinterpretation of preclinical progeria research suggests a hierarchical nuclear-vascular resilience framework with translational implications

Preclinical research traditionally advances through hypothesis-driven experimentation that establishes mechanistic pathways to support translational development. While this approach has generated major biological insights, it may underemphasize alternative organizational patterns embedded within complex datasets, parti...

P. Madeddu, Monica Cattaneo, A. Puca · 0 citations

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