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Author

P. Maillard

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Open access Oct 2026

Location matters: Attributing cognitive symptoms to white matter hyperintensities in 3,481 memory clinic patients.

BACKGROUND AND AIM In memory clinic patients, assessing diagnostic relevance of white matter hyperintensities (WMHs), as a marker to explain cognitive deficits, can be challenging. Here, we aimed to quantify this relevance by measuring the variance in cognitive function they explain, and consider, beyond total WMH volu...

Ewoud J. van der Lelij, Mirthe Coenen, F. de Kort et al. · 1 citation
Open access Sep 2026

Are the factors associated with cognitive performance generalizable across cohorts?

Tau pathology in the presence of Aβ was a stronger predictor of cognition in ADNI than in U.S. POINTER, and this discrepancy was not explained by increased vascular risk or brain atrophy in U.S. POINTER.

Pei-Wei Liu, Theresa M. Harrison, H. Snyder et al. · 0 citations
Open access Aug 2026

Beyond amyloid: Contributions of neuroinflammation, cerebrovascular disease, and neurodegeneration to memory impairment in the oldest‐old, the LifeAfter90 Study

It is hypothesized that elevated neuroinflammation, indicated by reactive astrocytosis, acts on cerebrovascular disease and separately, on amyloid beta (Aβ) pathology, to promote downstream medial temporal lobe atrophy and memory impairment.

Batool M. Rizvi, P. Maillard, A. Posis et al. · 0 citations

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