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Author

P. Meyre

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Open access Oct 2026

Integrated multiomic scores for cardiovascular disease prediction across multiancestral populations

Background: Genomic, epigenomic, and proteomic data capture complementary aspects of cardiovascular disease biology, but the value of integrating these data for predicting multiple cardiovascular disease outcomes across ancestry groups remains uncertain. Methods: We derived disease-specific proteomic scores using 999 p...

P. Meyre, M. Chong, M. Pigeyre et al. · 0 citations
Open access Oct 2026

Epigenetic scores and aging clocks capture mortality risk in heart failure

Current prognostic tools for heart failure (HF) rely mainly on clinical parameters and often fail to reflect the biological heterogeneity underlying patient outcomes. DNA methylation (DNAm)-based aging clocks and trait-specific epigenetic scores capture biological age and cumulative lifestyle and environmental ex...

P. Meyre, M. Chong, P. Joseph et al. · 0 citations
Open access Sep 2026

Epigenetic signatures of biological vulnerability and residual risk in heart failure

Higher epigenetic age and DNAm scores for CRP, frailty, and mortality were associated with increased risk, whereas higher diet-related DNAm scores were inversely associated, particularly for all-cause death.

P. Meyre, M. Chong, E. Shemesh et al. · 0 citations

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