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Author

P. Navarro-Santos

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2 papers indexed here

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Open access Oct 2026

Evaluation of Dihydropyridine Derivatives as Aldose Reductase Inhibitors: Enzymatic Screening, Molecular Docking and Ex Vivo Assessment of a Selected Compound in a Lens Model

Aldose reductase (AR) is a key enzyme in the polyol pathway and has been widely implicated in the development of diabetic complications, including cataract formation. In this work, a series of structurally modified 1,4-dihydropyridine (DHP) derivatives were evaluated as potential AR inhibitors. The compounds were obtai...

K. L. Alonso-Hurtado, Tania Méndez-Pérez, Z. Hernández-Gallegos et al. · 0 citations
Open access Sep 2026

Molecular Insights Into the Role of the Gallate Moiety in Catechin Derivatives as Inhibitors of Wild‐Type and Mutant Dihydrofolate Reductases From Staphylococcus aureus

Catechins are flavonoids characterized by aromatic rings and multiple hydroxyl groups. Green tea is one of the richest natural sources of these compounds and has been associated with several beneficial therapeutic effects. In this study, the inhibitory potential of the principal catechins found in green tea, along...

R. Santana-García, Pedro Palomares-Baez, J. Aviña-Verduzco et al. · 0 citations

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