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Who can benefit from percutaneous left atrial appendage closure? Recent advances.
Atrial fibrillation (AF) confers a substantial risk of stroke. Direct oral anticoagulants (DOACs) are highly effective for stroke prevention and form the cornerstone of AF management. Nevertheless, many eligible patients do not receive or do not maintain long-term anticoagulation because of bleeding risk, prior hemorr...
Atrial Fibrillation Burden and Clinical Outcomes After Catheter Ablation vs Lifestyle Modification With Antiarrhythmic Drugs
Background PRAGUE–25 compared catheter ablation (CA) with lifestyle modification combined with antiarrhythmic drugs (LFM + AADs) in obese patients with atrial fibrillation (AF). Objectives The objective of the study was to evaluate: 1) AF burden; and 2) clinical outcomes in CA vs LFM + AAD per-protocol populations enro...