Level of interleukine-10 and -22 in the blood and tissues of patients with medullary and papillary thyroid carcinomas
Background. Tumor-immune interactions critically shape thyroid cancer progression. Among immunoregulatory cytokines, interleukin-10 (IL-10) and IL-22 exert paradoxical functions by suppressing anti-tumor immunity while promoting tumor cell survival and metastasis (Mts). Yet the tissue-systemic distribution and metastat...