Sesamin Attenuates Interleukin-1β-Induced Inflammation in Human Synovial Cells: Involvement of the Nrf2/HO-1 Pathway and NLRP3 Expression
Osteoarthritis (OA) is a progressive joint disease characterized by cartilage destruction and is increasingly recognized as involving chronic low-grade inflammation. Synovitis contributes to OA progression through the production of proinflammatory mediators and reactive oxygen species (ROS). Sesamin, a lignan derived...