P. Saengdet

Silsesquioxane-Based and Hydroxyapatite-Containing Hybrid Biomaterials for Bone Regeneration: Evidence, Limitations, and Future Directions

The repair of critical bone defects remains a substantial clinical challenge. A regenerative material must support osteogenesis, provide appropriate mechanical function, and degrade at a rate compatible with tissue formation. Hydroxyapatite (HA) is osteoconductive and chemically similar to bone mineral, but its brittle...