Author

P. Sansone

2 papers indexed here

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Review Open access Sep 2026

The Predictive Paradigm in Perioperative Hemodynamic Management: The Role of Artificial Intelligence in Major Spine Surgery

Background: Major spine surgery carries an inherent risk of hemodynamic instability due to prone positioning, significant blood loss, and the strict necessity to maintain adequate spinal cord perfusion. Hemodynamic management mainly relies on a reactive approach, treating hypotension only after it occurs, which increas...

Gianluigi Cosenza, Marco Fiore, R. Giurazza et al. · Journal of Clinical Medicine · 0 citations

Review Open access Oct 2026

Pharmacokinetic/Pharmacodynamic Optimization and Therapeutic Drug Monitoring of Beta-Lactam Antibiotics in Abdominal Sepsis: Current Evidence, Challenges, and Clinical Perspectives—A Narrative Review

Background: Abdominal sepsis is associated with profound pharmacokinetic (PK) alterations that make standard beta-lactam dosing regimens potentially inadequate in critically ill patients. Increased volume of distribution, hypoalbuminemia, augmented renal clearance (ARC), acute kidney injury (AKI) and the PK complexity...

R. Giurazza, Gianluigi Cosenza, Marco Fiore et al. · Journal of Clinical Medicine · 0 citations