Pegah Seif

Thalamic Reticular Nucleus Dysfunction as a Stage-Dependent Integrative Circuit Mechanism in Psychosis.

This review argues that TRN dysfunction may help explain how cellular abnormalities, sleep-spindle deficits, thalamocortical dysconnectivity, and clinical symptoms become linked across the psychosis spectrum and proposes a stage-dependent model in which early TRN dysfunction contributes to subtle sensory and cognitive...