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P. Soluyanova

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Open access Jul 2026

The aryl hydrocarbon receptor is downregulated in MASLD while its activation attenuates steatosis in human hepatocytes through an IGFBP1-associated pathway.

It is demonstrated that AHR expression and its canonical activity-assessed by CYP1A1 mRNA levels-are inversely correlated with hepatic steatosis, and activation of this pathway may be taken into account in the therapeutic approaches for MASLD.

Marta Del Pozo-Medina, P. Soluyanova, Eugenia Pareja et al. · 0 citations

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