P. Tan

Artificial intelligence-guided engineering of a thermostable cellulase cocktail enables efficient biomass hydrolysis at elevated temperatures.

Efficient lignocellulosic biomass conversion under industrially relevant high temperatures is limited by the thermolability of commercial cellulases and a lack of synergistic, system-level thermostable cocktails. To address this gap, a thermostable cellulase cocktail comprising the endoglucanase TpEG, the cellobiohydro...