Author

P. Tarlykov

3 papers indexed here

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Open access Oct 2026

CHARACTERIZATION OF THE YELLOW FEVER VIRUS REPLICATION COMPLEX USING AN NS1–GFP REPLICON

Yellow fever virus is a mosquito-borne flavivirus responsible for severe human disease. Flaviviruses cause an estimated 400 million infections annually worldwide and are transmitted between animals and humans via arthropod vectors. Viral RNA replication is mediated by non-structural proteins that assemble into membrane...

D. Auganova, S. Atavliyeva, B. Ingirbay et al. · Eurasian journal of applied... · 0 citations

Open access Aug 2026

Rapid detection of Streptococcus agalactiae using an RPA-MbCas12a CRISPR assay targeting novel sodA and groL markers

Streptococcus agalactiae (Group B Streptococcus, GBS) is a major cause of neonatal and invasive infections, necessitating rapid and sensitive diagnostic approaches beyond conventional culture and PCR. Here, we developed an isothermal recombinase polymerase amplification (RPA)-MbCas12a CRISPR assay for fluorescence-base...

A. Shamukhan, A. Shaizadinova, M. Amanzholova et al. · Frontiers in Microbiology · 0 citations

Open access Aug 2026

Integrated NGS and ddPCR analysis of RAS/RAF mutations in metastatic colorectal cancer among Kazakhstani patients: a pilot study

Background Colorectal cancer (CRC) is one of the leading causes of cancer-related morbidity and mortality worldwide, and metastatic colorectal cancer (mCRC) is associated with poor prognosis and limited treatment options. Mutations in the KRAS, BRAF oncogenes are key molecular drivers of colorectal cancer development a...

G. Kulmambetova, P. Tarlykov, D. Auganova et al. · Frontiers in Medicine · 0 citations