Casein kinase 1 (CK1) and casein kinase 2 (CK2) are highly conserved serine/threonine protein kinases that regulate multiple oncogenic signaling pathways involved in cancer progression, metastasis, and therapeutic resistance. Overexpression or dysregulation of CK1 and CK2 has been shown to contribute to the development...
P. Waghmare, A. Chabukswar, K. Raut et al.· Mini-Reviews in Medical Chem...· 0 citations
AI-driven approaches in transcription modulator discovery are highlighted, including in silico target identification, multi-omics integration, and structure–activity optimization, and the importance of explainable AI and personalised therapeutics in advancing precision medicine and next-generation transcription-based d...
A. Pimpale, P. Waghmare, Pallavi Zode et al.· Journal of Applied Pharmaceu...· 0 citations
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