Author

P. Wellendorph

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Open access Sep 2026

Sex-dependent investigations of the temporal development of infarct size and blood-brain barrier permeability after photothrombotic stroke in mice - a pilot study.

Findings indicate that BBB permeability, but not infarct size, is influenced by sex in the photothrombotic stroke model, which warrants further investigations into potential sex differences in BBB permeability as well as other potential consequences of stroke.

Maria Thaysen, Natalia Łopuszyńska, E. Westi et al. · Brain Research · 0 citations

Open access Oct 2026

Development of a NanoBRET assay platform to detect intracellular target engagement in living cells for the Glycine Transporter 1 (SLC6A9)

Glycine transporter 1 (GlyT1) is a clinically investigated target whose conformational plasticity enables ligands to engage distinct extracellular and intracellular binding sites. However, methods to directly quantify intracellular binding remain limited and largely rely on radioligand-based approaches. Here, we report...

M. H. Jensen, Ioannis P. Avgeris, N. Kocaturk et al. · bioRxiv · 0 citations