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P. Weydt

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Open access Sep 2026

Interaction- and asymmetry-aware facial blendshape analysis for objective quantification of Parkinsonian hypomimia

Reduced facial expressivity (hypomimia) is an early motor feature of Parkinson’s disease (PD), yet its assessment still relies on subjective, coarse-grained clinical scales. Using ExpressionTracker, a consumer-grade application built on Apple’s ARKit framework, we derived 261 facial expression features during standardi...

B. Koyak, Timo Menzel, M. Rodemann et al. · 0 citations
Open access Jul 2026

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

The results suggest that TnT and sNfL capture different dimensions of disease status within the D50 framework, and further longitudinal studies are needed to determine whether combining these biomarkers improves disease stratification or prognostic assessment in clinical practice and therapeutic trials.

Julia Sellin, Sofia Waldorf, Janina von der Gablentz et al. · 0 citations
Open access Jul 2026

Multiplex Panel Detects Glial and Inflammatory Biomarker Signatures in Sporadic and C9orf72-ALS

The NULISA multiplex platform supports the use of a multiplexed panel of diverse, inflammatory, glial, and neurodegeneration-associated biomarkers as a complementary diagnostic and prognostic tool alongside established measurements of neurofilaments.

Karthik Baskar, Christina Steffke, S. Bernsen et al. · 0 citations

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