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Author

Pablo F. Castro

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Open access Oct 2026

microRNA-15b modulates stress-induced premature senescence in chronic doxorubicin cardiomyopathy

Doxorubicin (DOX) is the most widely used anthracycline in hematologic and solid tumors, whose clinical utility is constrained by dose-dependent cumulative cardiotoxicity that can progress to chronic heart failure. Although previously attributed to overt cardiomyocyte loss, emerging evidence indicates that stress-i...

Georthan Mancilla, C. Quiroga, Pablo F. Castro et al. · 0 citations

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