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Author

Pamela M. Martin

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Open access Oct 2026

Loss of Farnesoid X Receptor Signaling Promotes Choroidal Neovascularization in Mice

Choroidal neovascularization (CNV) is a defining feature of neovascular age-related macular degeneration (nAMD). Although anti-vascular endothelial growth factor (VEGF) therapies suppress neovascular activity, incomplete responses, recurrent leakage, and subretinal fibrosis remain important clinical challenges. The far...

Chanel Harris, M. Nisar, Ankit Seth et al. · 0 citations
Review Open access Sep 2026

Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling

ABSTRACT Short‐chain fatty acids (SCFAs) have emerged as key molecular mediators of gut–eye communication, linking microbial metabolism to ocular physiology and disease. Produced through microbial fermentation of dietary fiber, SCFAs function as systemic signaling molecules that regulate immune homeostasis, metabolic f...

Aleah J. Brokemond, Ronny Amamoo, Fapianey J. Alexandre et al. · 0 citations

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