Sodium L-lactate alleviates DSS-induced colitis through gut microbiota remodeling and Akkermansia enrichment.
L-lactate, a byproduct of glycolysis and hypoxia, accumulates in the gut during disease progression and may affect host responses and microbial metabolism. Here, we investigated the protective effect of sodium L-lactate on dextran sulfate sodium (DSS)-induced colitis in mice and the involvement of the gut microbiota. O...