Diabetes-associated cognitive impairment is closely linked to hippocampal neuroinflammation, but effective treatments remain limited. This study investigated the protective effects of agomiR-31-5p against cognitive dysfunction and neuroinflammatory injury in db/db mice. Male db/db mice received agomiR-31-5p via tail-ve...
Zhi-Ying Zou, Jia-Hui Zhao, Wan-Zhen Han et al.· Experimental Neurology· 0 citations
Alzheimer's disease (AD) remains one of the most challenging neurodegenerative disorders, primarily due to the lack of reliable tools for its early and non-invasive diagnosis. Exosomes, nanosized extracellular vesicles secreted by neural and peripheral cells, have emerged as promising biomarkers reflecting the molecula...
Jinjin Pei, N. Perumal, Pan-Pan Meng et al.· Ageing Research Reviews· 1 citation
Skin wound healing remains a prominent clinical challenge, creating an urgent demand for high-performance wound-care biomaterials. Deaminotyrosine (DAT), a recently identified flavonoid-derived gut metabolite, exhibits anti-inflammatory and immunomodulatory activities. Nevertheless, its translational application is gre...
Zheng-Yuan Li, Jin Yang, Xiao-Wen Peng et al.· Journal of materials chemist...· 0 citations
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