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Pan-Woo Ko

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Review Open access Aug 2026

Fluid and Imaging Biomarkers in Lecanemab Therapy for Early Alzheimer’s Disease: Current Evidence, ARIA Risk Prediction, and Treatment Monitoring

Background/Objectives: Lecanemab, a humanized anti-amyloid-β protofibril antibody, achieves substantial amyloid clearance and modest slowing of clinical decline in early Alzheimer’s disease (AD). Amyloid-related imaging abnormalities (ARIA) represent the most clinically important safety concern, yet no fluid biomarker...

Pan-Woo Ko · 0 citations

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