Structure-based Drug Design and Pharmacokinetic Profiling of Novel Heterocyclic Androgen Receptor Inhibitors for Prostate Cancer Treatment
Prostate cancer is one of the most prevalent malignancies and the second leading cause of cancer-related death in men after cardiovascular diseases. Currently available therapies, such as bicalutamide, suffer from limitations, including off-target effects and resistance, highlighting the urgent need for novel andro...