Open access
Aug 2026
KDM4C inhibition reinforces NK cell cytotoxicity through the cGAS-STING pathway in TP53-mutated AML.
It is demonstrated that pharmacological KDM4C inhibition with QC6352 induces cellular senescence and enhances the intrinsic immunogenicity of TP53-mutated AML cells through activation of the cGAS-STING pathway.
Xinyi Zhang, Hui-Lan Liu, L. Geng et al.
· Aging and Disease · 0 citations