A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer
A bioinspired nanoplatform is presented that co‐delivers manganese peroxidase (MnP) and Mn 2+ /Mn 3+ ions to synergistically trigger ferroptosis and activate the cGAS–STING pathway, establishing a “catalytic immunotherapy” paradigm that leverages fungal enzymatic activity for systemic cancer treatment.