Inhibition of NOX2 Prevents Impairment of Cardiovascular Response and Inflammatory Tissue Injury Mediated by Nitrosative/ Oxidative Stress in the Lipopolysaccharide-Induced Septic Shock Model in Rats.
INTRODUCTION It is unknown whether inhibition of nicotinamide adenine dinucleotide phosphate oxidase (NOX) 2 has protective effects against the impaired cardiovascular response and inflammatory tissue injury mediated by nitrosative/ oxidative stress in bacterial septic shock. Therefore, using the NOX2 inhibitor NOX2ds-...