Open access
Sep 2026
miRNA Isoform Spectrum Expansion by Overexpression May Affect Target Gene Silencing.
MicroRNAs (miRNAs) regulate gene expression primarily through translational inhibition and mRNA degradation. Their functional complexity is increased by the presence of various mature isoforms (isomiRs). These isomiRs add diversity to miRNA targeting and regulation, yet their impact on cellular systems remains insuffic...
Fabian Kern, Martin Hart, Lena Krammes et al.
· Genomics, Proteomics & Bioin... · 0 citations