Open access
Aug 2026
Genome-wide transcriptional landscape of Mycobacterium tuberculosis during acute lung infection
Tuberculosis (TB) remains a major global health burden, yet the mechanisms by which Mycobacterium tuberculosis (Mtb) adapts to host environments to drive disease pathology are incompletely defined. A key limitation has been reliance on axenic culture systems that fail to recapitulate the complex, host-imposed stresses...
Gunapati Bhargavi, Saleena Ghanny, Patricia Soteropoulous et al.
· Frontiers in Immunology · 0 citations